Abstract Background During kidney organogenesis, metanephric mesenchyme (MM) and ureteric bud (UB) interact reciprocally to form nephrons.Signaling stimuli involved in these interactions include Wnts, growth factors and nano/micro particles.How UB and MM are interacting is not completely understood.Our study investigated the signaling and communica
gift_wrapping BackgroundHuman epidermal growth factor receptor 2(HER-2) is the most prominent therapeutic target for gastric (G)/gastroesophageal junction (GEJ) cancer.Guidelines recommend its use for treating G/GEJ cancers.However, targeted therapy did not significantly improve survival outcomes compared to those with neoadjuvant therapy.The KEYNO
In this paper, the effect of some design parameters on the kinematiccharacteristics (displacement, velocity, and acceleration)of the external and internal Geneva Mechanism (GM) has been considered analytically using MATLAB and numerically using SolidWorks program.The parameters, such asthe change of: the drive pin diameter or the width of slot orth
Background: Metastatic breast cancer (MBC) patients with low expression of human epidermal growth factor 2 (HER2) have been proven to benefit from HER2 targeted therapy.We aimed to determine how HER2-low status affected survival and metastatic risk as well as how it affected pathological complete response Face and body wash (pCR) in neoadjuvant che